PROGRAMME

Thursday June 8, 2006

8.30
Participants registration

8.50
Welcome to participants

RENAL DEVELOPMENT AND RELATED DISORDERS (Coordinator: S. Vainio)

9:00
Kidney as a developmental model system - S. Vainio

9:45
Development of urinary tract - C. Mendelsohn

10:30
Break

ANIMAL MODELS OF RENAL DISEASE

11:00
The production of animal models with chemical mutagens: phenotype and genotype driven strategies - J. L. Guenet

11:45
Targeted mutagenesis in embryonic stem cells as a way to create animal models of human diseases - C. Babinet

12:30
Lunch

GENOMIC AND PROTEOMIC TOOLS TO INVESTIGATE THE GENETIC BASIS OF RENAL DISEASES (Coordinator: R. Ravazzolo)

14:00
Introduction to genomic tools - R. Ravazzolo

14:45
Genomic approach to the study of kidney and ureteral tract malformations - A. G. Gharavi

15:30
Introduction to proteomic tools - G. Candiano

16:15
Break

16:45
Urinary proteins - L. Musante

17:30
What is new on renal cell carcinoma proteome - C. Sarto

Friday June 9, 2006

GENETICS OF GLOMERULAR AND TUBULAR DISORDERS - (Coordinator: C. Antignac, M. Konrad)

8:45
Genetics of nephrotic syndrome - C. Antignac

9:30
Alport syndrome and benign familial hematuria - R. Torra

10:15
Hereditary hemolitic-uremic syndrome - C. Loirat

11:00
Break

11:30
Tubular disgenesis and the renin-angiotensin system - M. G. Gubler

12:15
Genetics of hypomagnesemia - M. Konrad

13:00
Lunch

14:00
Genetics of hypophosphatemic rickets - C. Fluck

14:45
Nephrogenic diabetes insipidus: do pharmacochaperones provide the cure? - P. Deen

CYSTIC RENAL DISEASES

15:30
Spatial and functional regulation of the polycystin complex - A.C. Ong

16:15
Break

16:45
Developmental and postnatal function of HNF1 alpha and beta - M. Pontoglio

17:30
The role of polycystin in renal tubulogenesis - A. Boletta

Saturday June 10, 2006

MALFORMATIVE SYNDROMES (Coordinator: N. Knoers)

8:45
Malformative syndromes with renalinvolvement - N. Knoers

9:30
FRAS/FREM gene mutations cause human and mouse Fraser syndromes and lead to renal aplasia and polycystic diseases - A. Woolf

10:15
Break

GENETIC BASIS OF TISSUE REGENERATION

10:45
Therapeutic perspective of stem cells - F. Frassoni

11:30
Stem cells in the adult kidney and their possible role in renal repair - Q. Al-Awqati

12:15
Concluding remarks

Final test

13:00
Lunch